Fig. 7
Cytokeratin expression in artificial skin 10 days after treatment; Immunohistochemical staining of cytokeratin indicating the distribution of keratin expression in keratinocytes and melanocytes from the indicated experimental group; negative control (a), non-treated group (b), sericin-treated with doses of 5 (c), 10 (d), and 20 (e) μg/mL comparing to non-immunostained skin (f). Tyrosinase was mainly labeled on the cytoskeletal components that are characterized by numerous of gold particles (g, h). Cytokeratin level was compared as shown in the bar graph (i)