Fig. 4
From: Improvement of endothelial function by Gunnera tinctoria extract with antioxidant properties
Effect of G. tinctoria on apoptotic gene Noxa, induced by high d-glucose and hydrogen peroxide. a Representative images of PCR products of Noxa and 28S obtained from HUVECs incubated with M199 and: 25 mM d-glucose (HG) or H2O2 in absence or presence of 200 μg/L of G. tinctoria extract (labeled as HG+G. tinctoria or H2O2 + G. tinctoria, respectively). b The intensity of amplicon images from three different experiments were analyzed and rate between Noxa and 28S was plotted to represent the effect of G. tinctoria on changes in Noxa expression in HUVECs. Values are mean ± SEM, n = 3. *p < 0.05 versus control or vehicle; **p < 0.01 versus control or vehicle; Фp < 0.05 versus high d-glucose; γp < 0.05 versus H2O2