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Fig. 4 | Biological Research

Fig. 4

From: LncRNA MALAT1 aggravates oxygen‐glucose deprivation/reoxygenation-induced neuronal endoplasmic reticulum stress and apoptosis via the miR-195a-5p/HMGA1 axis

Fig. 4

miR-195a-5p is essential for MALAT1-mediated neuronal function. a The expression of miR-195a-5p in HT22 cell treated with miR-195a-5p inhibitor by qRT-PCR. HT22 cells under OGD/R condition were treated with si-MALAT1 or cotreated with si-MALAT1 and miR-195a-5p inhibitor, and then subjected to (b) CCK-8 assay for cell viability. c Flow cytometry analysis for cell apoptosis. d Western blot of apoptosis-related proteins. e, Western blot of GRP78 and CHOP proteins. *p < 0.05 vs. the OGD/R groups, #p < 0.05 vs. the si-MALAT1 groups

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Biological Research

ISSN: 0717-6287

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